Impact of malathion on the serum of albino rats
Research lab, Department of Chemstry, Narain(P.G.) College, Shikohabad UP India
*Department of Chemistry, Janta College Bakewar UP India
Organophosphorus pesticides are mainly used in crop protection. Malathion in itself has only a slight direct inhibitory effect on mammals erythrocyte cholinesterase (ChE) and non specific esterases but one of its metabolite `malaoxon' is an active inhibitor. In this study experiments were carried out on male albino rats weighing 175 ± 25 gm. Malathion was orally administered for 6 days in increasing doses of 150, 300, 600 and 900 mg/kg to each rat. After completing the time rats were sacrificed and serum was obtained. The activity of Glutamyl Oxalo acetic Transaminase (GOT) and Glutmayl Pyruvate Transaminase (GPT) were studied for toxicological effect on the blood serum. Malathion treatment caused increase in serum GOT and GPT activity.
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B.K. Srivastava, Arvind Kumar and Grish Chandra* , "Impact of malathion on the serum of albino rats ", Journal of Ultra Chemistry, Volume 7, Issue 3, Page Number 419-422, 2016Copy the following to cite this URL:
B.K. Srivastava, Arvind Kumar and Grish Chandra* , "Impact of malathion on the serum of albino rats ", Journal of Ultra Chemistry, Volume 7, Issue 3, Page Number 419-422, 2016Available from: http://www.journalofchemistry.org/paper/522/
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