Isonicotinic acid hydrazide (INH) when condensed with carbon disulphide in ethanolic potassium hydroxide yielded potassium dithiocarbazinate (2). On heating (2) and acid hydrazide yielded compounds (3 a-I). The compounds (3a-1) were reacted with 2,3- dichloroquinoxaline and yielded compounds (4a-I). The antifungal and antibacterial activity of the compounds have also been evaluated. The structures of the new compounds were established on the basis of analytical and spectral data.