Atenolol [RS),4-{2-hydroxy-3-isopropylaminopropoxy}phenylacetamide] is an antihypertensive drug, used primarily in cardiovascular diseases. The simple complexes of this drug with Pb(II) have been studied by direct current polarography at 25°C and 35°C. The reduction of all complexes is found to be reversible and diffusion controlled involving 2e^_ in each case. Deford and Hume's treatment suggests that Atenolol forms 1 : 2 complexes (metal to ligand molar ratio) at 25°C and 35°C. Two very stable complexes PbR⁺ and PbR₂ are identified at two temperatures at µ = 1 (1M KNO₃). The values of overall formation constant (log b) obtained are 4.8448, 7.8644 at 25°C and 4.6976, 7.6732 at 35°C. The thermodynamic parameters (DG°, DH°, DS°) have also been reported.