Waste which is generated during the medical research work, production and testing of biological diagnosis, treatment or immunization of human being and animals termed as "hospital waste" Improper handling and management of Hospital waste can spread infection and pollute air, water and soil. When infections hospital waste mixed with general non infections waste or municipal waste it makes the whole waste infectious Improper treatment of infectious hospital waste can also spread infection and communicable diseases among the hospital employees, patients municipal workers and general public. Hospital waste can also cause diseases like AIDS, hepatitis B & C, skin infection etc. Reuse of disposable items, needles, catheters, IV-sets and dialysis sets is also a major problem which must be solved within time. So it is important to adopt proper scientific methods of waste handling, management and its safe disposal or recycling. The present paper discussing the problem of hospital waste management in Bhopal city and management strategy to be adopted to solve this problem.