Anti-inflammatory and analgesic activity of N-aryl-2-[(2-aryl-1, 3-benzoxazol-5-yl) carbonyl] hydrazine carbothioamides
Author & Affiliation:
NADEEM SIDDIQUI
Department of Pharmaceutical Chemistry, Faculty of Pharmacy: Jamia Hamdard (Hamdard University) Hamdard Nagar, New Delhi - 110062 (INDIA)
M. SARAFROZ
Department of Pharmaceutical Chemistry, Faculty of Pharmacy: Jamia Hamdard (Hamdard University) Hamdard Nagar, New Delhi - 110062 (INDIA)
M. FAIZ ARSHAD
Department of Pharmaceutical Chemistry, Faculty of Pharmacy: Jamia Hamdard (Hamdard University) Hamdard Nagar, New Delhi - 110062 (INDIA)
M. MUMTAZ ALAM
Department of Pharmaceutical Chemistry, Faculty of Pharmacy: Jamia Hamdard (Hamdard University) Hamdard Nagar, New Delhi - 110062 (INDIA)
ASIF HUSAIN
Department of Pharmaceutical Chemistry, Faculty of Pharmacy: Jamia Hamdard (Hamdard University) Hamdard Nagar, New Delhi - 110062 (INDIA)
Keyword:
Benzoxazole, Phenylisothiocyanates, Anti-inflammatory and analgesic activities.
Issue Date:
April 2009
Abstract:
A series of N-aryl-2-[(2-aryl-1, 3-benzoxazol-5-yl) carbonyl] hydrazine carbothioamides (4a-p) were synthesized on refluxing 2-aryl-1, 3-benzoxazole-5-carbohydrazides with aryl isothiocyanates starting from methyl-4-hydroxy-3-amino benzoate via synthesis of intermediate 2-aryl-1, 3-benzoxazole-5-carbohydrazides. The compounds were characterized by 1H NMR, IR spectra and by means of C, H, and N analysis.
Key words : Benzoxazole, Phenylisothiocyanates, Anti-inflammatory and analgesic activities.
Pages:
1-6
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
PDF:
DOI:
juc
Copy the following to cite this article:
N. Siddiqui; M. Sarafroz; M. F. Arshad; M. M. Alam; A. Husain, "Anti-inflammatory and analgesic activity of N-aryl-2-[(2-aryl-1, 3-benzoxazol-5-yl) carbonyl] hydrazine carbothioamides ", Journal of Ultra Chemistry, Volume 5, Issue 1, Page Number 1-6, 2018Copy the following to cite this URL:
N. Siddiqui; M. Sarafroz; M. F. Arshad; M. M. Alam; A. Husain, "Anti-inflammatory and analgesic activity of N-aryl-2-[(2-aryl-1, 3-benzoxazol-5-yl) carbonyl] hydrazine carbothioamides ", Journal of Ultra Chemistry, Volume 5, Issue 1, Page Number 1-6, 2018Available from: http://www.journalofchemistry.org/paper/670/
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