Journal of Chemistry

Papers

Voulume: 10
Issue: 3
Article No. 1
Study to Find Out Suitability of Water Extract of Catharanthus Roseus Flowers as Indicator for Acid-Base Titrations
MAYUR C. SHAH*a, GUNJAN K. SAKHIYAa and PRATEEK G. SHILPKARb

aDepartment of Microbiology, Gujarat Vidyapith Sadra Dist-Gandhinagar Gujarat India

bBiogas Research and Extension Centre, Gujarat Vidyapith Sadra Dist-Gandhinagar Gujarat India

cAssistant Professor Biogas Research and Extension Centre Gujarat Vidyapith Sadra Dist-Gandhinagar Gujarat India

Email:- mayurchemistry@yahoo.co.in

 

Abstract :

A laboratory experiment was conducted to find out the suitability of water extract of Catharanthus roseus flowers as indicator in different acid-base titrations viz strong acid v/s strong base (0.01, 0.1 and 1M HCl with same concentration of NaOH); weak acid v/s strong base (0.1M CH3COOH with 0.1M NaOH); and weak base v/s strong acid (0.1M NH4OH with 0.1M HCl). The water extract was obtained by simple boiling of 10%w/v solution of Catharanthus roseus flowers in distilled water. The color change of water extract of flower at different pH values was find out pH metrically and for standardization it was compared with phenolphthalein (1% w/v in ethanol) and methyl orange (1% w/v in ethanol) for the same system. The theoretical values of pH at various stages were compared with pH change of natural indicator in this range. Results reveal that the water extract of Catharanthus roseus flowers shows the color change at the equivalence point for HClNaOH and NH4OHHCl titration but it failed to produce color change at equivalence point for CH3COOHNaOH titration.

Keyword :
DOI : juc
Paper Download Count : 1079
View Count : 756
Share
Facebook Twitter Google Plus LinkedIn Reddit
Article No. 2
Synthesis and Evaluation of Some Novel Pyrazoles for Antinflammatory Studies
BRIJENDRA KUMAR SONI*1, G. DEVALA RAO2 and SHANTHARAM UMESH NAYAK3

1MES College of Pharmacy, Bangalore india

2KVR Siddartha College of Pharmacy, Vijayawada India

Government College of Parmacy, Bangalore India

Email:- bksoni19@gmail.com

Abstract :

A series of novel pyrazoles were synthesized starting from 4- fluoro-3-chloroaniline by condensation with aromatic aldehydes to give chalcones which were cyclized with hydrazine to obtain pyrazoles. The chlorine replaced various aromatic amines to obtain the final derivatives. The final compounds evaluated for in vitro bovine serum denaturation assay and in vivo antinflammatory activity by carrageenan induced rat paw oedema. The study indicated the importance of chlorine at the para position of the aromatic ring in enhancing antiinflammatory activity. Correlation with enzyme inhibition scores also explained.

Keyword :
DOI : juc
Paper Download Count : 710
View Count : 659
Share
Facebook Twitter Google Plus LinkedIn Reddit
Article No. 3
pH Dependent Spectral Characteristics of Horseradish Peroxidase dissolved in Aqueous Buffer as well as in Nonionic Reverse Micellar Systems
ANIL KUMAR

Post Graduate Department of Chemistry College of Commerce, Patna India

Email:-anilcoc2013@gmail.com

Abstract :

In this article, the spectral characteristics of horseradish peroxidase in aqueous buffer as well as nonionic reverse micelles is reported at various pH values. It is found that the soret band of HRP slightly shifted in acidic as well as in alkaline media with respect to the neutral pH( pH 7.00). The shifting of λmax could be related with the conformational change of the enzyme molecule at different pH values. Further, the absorption spectra of the peroxidase in aqueous buffer as well as in nonionic micellar media at Wo = 15, pH = 7.00, is found virtually unchanged. The molar extinction coefficient (ε) of peroxidase at λ = 403 nm remains more or less constant till pH 11.8 inside the aqueous pool of the reverse micellar system and above this it falls rapidly. The fall of εvalue indicates that there is a change of conformation of the enzyme molecule after pH 11.8

Keyword :
DOI : juc
Paper Download Count : 770
View Count : 538
Share
Facebook Twitter Google Plus LinkedIn Reddit
Article No. 4
Synthesis and Evaluation of Some Novel Pyrazoles for Antibacterial and Antioxidant Activity
BRIJENDRA KUMAR SONI*1, G.DEVALA RAO2 and SHANTHARAM UMESH NAYAK3

1MES College of Pharmacy, Bangalore india

2KVR Siddartha College of Pharmacy, Vijayawada India

3Government College of Parmacy, Bangalore India

Email:- bksoni19@gmail.com

Abstract :

A series of novel pyrazoles were synthesized starting from 4- fluoro-3-chloroaniline by condensation with aromatic aldehydes to give chalcones which were cyclized with hydrazine to obtain pyrazoles. The chlorine was replaced with various aromatic amines to obtain the final derivatives. Evaluation of antibacterial activity against Staphylococcus aureus and Escherechia coli highlights the importance of methyl substitution and requirement of high lipophilicity. Ferric ion reduction studies indicate the requirement of requirement of electron releasing aromatic substitutions for enhanced antioxidant activity

Keyword :
DOI : juc
Paper Download Count : 683
View Count : 669
Share
Facebook Twitter Google Plus LinkedIn Reddit
Article No. 5
Xanthium Plants, Boon for the Cancer
A.H. ANSARI

Professor Department of Chemistry

Gov. PG College , Damoh MP India

Abstract :

The Present paper deals the presence of potential antitumor activity of the compounds isolated from xanthium species of composite a family. Enough evidences prove that sesquiterpenoidal lactones present the above plants posses good anti cancerous reputation.

Keyword :
DOI : juc
Paper Download Count : 570
View Count : 722
Share
Facebook Twitter Google Plus LinkedIn Reddit
Article No. 6
E- Waste: Fastest Growing Hazardous Waste (A review)
KAVITA GOUR

Department of Applied Chemistry Priyadarshini JL college of Engineering new Nandanvan nagpur MS India

Abstract :

Waste of electronics/ electrical goods that have reached their end of life. Electronic products often contain hazardous and toxic materials and should not be dumped with other wastes. Along with China, India is largest importer of E-waste from developed countries like US; UK and Japan. In India 90% of mobile equipment are imported. The rate of e-waste generation is increasing by 10% every year1

Keyword :
DOI : juc
Paper Download Count : 620
View Count : 704
Share
Facebook Twitter Google Plus LinkedIn Reddit
Article No. 7
Determination of Formation Constant and Study of Thermodynamic parameters of transition metal complexes with Pyrazoline derivatives as ligand
PREM MOHAN MISHRA

Prof. & Head Department of Chemistry MLSM College Dharbhanga India

Abstract :

Trisubstituted Pyrazolines were prepared. Metal ligand stability constant of complex compounds of Co(II), Ni(II), Cu(II), Zn (II) & Cd (II) were determined by Calvin – Bjerrum pH metric titration technique modified by Irving & Rossotti at two temperatures ie. 303 K & 308 K in water : dioxane mixture in 1:1 ratio by volume. Ionic strength of the solution was kept constant (  0.1M) using NaNO3 solution. The values of stepwise stability constant log K1 & log K2 were calculated by half integral method and was further verified by mid point calculation method and linear plot method. The observed stability constant value are in the order Cd(II) < Zn (II) < Co(II) < Ni (II) < Cu (II). This result is in conformity with the Irving – Williams natural order of stability. The values of  G 0 and H 0 for all the metal chelates were found to be negative indicating that the chelate formation is a spontaneous process.

Keyword :
DOI : juc
Paper Download Count : 732
View Count : 614
Share
Facebook Twitter Google Plus LinkedIn Reddit
Ansari Education And Research Society
Facebook Google Plus Twitter
Secured Site