Cyclodehydration of thiocarbohydrazide with substituted benzoic acid gives, 5-Aryl-4-amino-3-mercapto-1,2,4 triazole. The requisite 3-Aryl-1,2,4-triazolo-8-methyl-thiadiazepin-6-ones were prepared by refluxing ethyl acetoacetate and 5-Aryl-4-amino-3-mercapto-1,2,4-triazole. The screening results are correlated with the structural features of the tested compounds.
Copy the following to cite this article:
H. Singh; S. Singh, "Synthesis of some antimicrobial 3-Aryl-1,2,4- triazolo-8-methyl-thiadiazepin-6-ones ", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 41-44, 2018Copy the following to cite this URL:
H. Singh; S. Singh, "Synthesis of some antimicrobial 3-Aryl-1,2,4- triazolo-8-methyl-thiadiazepin-6-ones ", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 41-44, 2018Available from: http://www.journalofchemistry.org/paper/803/