Preparation, Characterization, Dissolution and Bioavailability of Hg(II) with Sulfathiazole
The interaction of sulfa drug sulfathiazole (STZ) with mercury(II) has been analyzed and solid complex was isolated and characterized by elemental and thermal analysis, FT-IR, 1H NMR spectral and electrical conductivity measurements. These studies suggest that the coordination of Hg(IIl with the Nthiazole atom forms stable STZ-Hg(II) complex. The structure of formula Hg(CTZ)2 complex has been proposed. The complex was screened for its activity against Escherichia coli and other microorganisms, showing an appreciable antimicrobial activity with the ligand. We observe greater dissolution rate of complex than pure STZ.
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P. Kumar; V. Arora; R. N. Sharma, "Preparation, Characterization, Dissolution and Bioavailability of Hg(II) with Sulfathiazole", Journal of Ultra Chemistry, Volume 3, Issue 2, Page Number 153-158, 2018Copy the following to cite this URL:
P. Kumar; V. Arora; R. N. Sharma, "Preparation, Characterization, Dissolution and Bioavailability of Hg(II) with Sulfathiazole", Journal of Ultra Chemistry, Volume 3, Issue 2, Page Number 153-158, 2018Available from: http://www.journalofchemistry.org/paper/655/
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