Journal of Chemistry

Novel modification in the structure of well-known Drug Ciprofloxacin

Author & Affiliation:
Pradeep Yadav (pradeepyadav78@gmail.com
Department of Chemistry, University of Rajasthan, Jaipur - 302004 (Rajasthan) INDIA
Usha Baloda
Department of Chemistry, University of Rajasthan, Jaipur - 302004 (Rajasthan) INDIA
Y.C. Joshi
Department of Chemistry, University of Rajasthan, Jaipur - 302004 (Rajasthan) INDIA
Keyword:
spectral studies viz, derivative again
Issue Date:
December 2007
Abstract:

Reaction of [1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7- (1-piperazinyl)-quinolone-3-carboxylic acid with diazoazonium salt of 2-aminopyridine in acetonitrile to get 1-cyclopropyle-6-fluoro-4-oxo-7-[4-(pyridine-2-yldiazenyl)-piperazin-1-yl]-1,4-dihydro-quinoline-3-carboxylic acid derivative. This ciprofloxacin derivative again subjected to react with various -diketone in presence of sodium methoxide to get novel -diketone derivative of 1-cyclopropyle-6-fluoro-4-oxo-7-[4-(pyridine-2-yldiazenyl)-piperazin-1-yl]-1,4-dihydro-quinoline-3-carboxylic acid. Structures of these compounds were established on the basis of spectral studies viz. IR, 1H NMR etc.    

 

Pages:
137-140
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
DOI:
juc

Copy the following to cite this article:

P. Yadav; U. B. ; Y. Joshi, "Novel modification in the structure of well-known Drug Ciprofloxacin", Journal of Ultra Chemistry, Volume 3, Issue 2, Page Number 137-140, 2018

Copy the following to cite this URL:

P. Yadav; U. B. ; Y. Joshi, "Novel modification in the structure of well-known Drug Ciprofloxacin", Journal of Ultra Chemistry, Volume 3, Issue 2, Page Number 137-140, 2018

Available from: http://www.journalofchemistry.org/paper/651/

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