Application of Novel Clay catalyst for the Synthesis of bis-indole derivatives from 2-phenyl-1-H- indole
1Post Graduate and Research Centre, Maulana Azad College, Aurangabad (M.S.)
2P. G. Department of Chemistry, Shri Anand College Pathardi, Dist. Ahmednagar (M.S.)
3Dr. Rafiq Zakaria College for Womens, Navkhanada Aurangabad, Dist. Aurangabad, (M.S.)
4Government College of Arts and Science Aurangabad, Dist. Aurangabad, (M.S) India
Email address of Corresponding Author: abed3dec@gmail.com, mazahar_64@rediffmail.com
In this study, we report that the novel clay material was found to catalyze electrophilic substitution reaction of 2-phenyl-1-H-indoles with a variety of aromatic aldehydes to excellent yields of bis (indolyl) methanes at room temperature. The efficient synthesis of 2-phenyl-1-H-indoles was achieved by Fischer indole synthesis with addition of phenyl hydrazine and acetophenone.
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ISMAIL SHAIKH* 1, 2, MUKTAR SHAIKH2, MAZAHAR FAROOQUI3 and SYED ABED4, "Application of Novel Clay catalyst for the Synthesis of bis-indole derivatives from 2-phenyl-1-H- indole", Journal of Ultra Chemistry, Volume 13, Issue 2, Page Number 25-29, 2017Copy the following to cite this URL:
ISMAIL SHAIKH* 1, 2, MUKTAR SHAIKH2, MAZAHAR FAROOQUI3 and SYED ABED4, "Application of Novel Clay catalyst for the Synthesis of bis-indole derivatives from 2-phenyl-1-H- indole", Journal of Ultra Chemistry, Volume 13, Issue 2, Page Number 25-29, 2017Available from: http://www.journalofchemistry.org/paper/543/
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