Journal of Chemistry

Role of Molecular Redundancy in modeling carbonic anhydrase (CA-IV) inhibition

Author:
M.L. GANGWAL1, and SHWETA(Thakur)RATHORE*2
Affiliation:

Department of Chemistry P.M.B Gujarati College Indore India

Email:-shweta_rathore02@yahoo.com.

Keyword:
Issue Date:
April 2013
Abstract:

In a previous article we deal with the QSAR model of water soluble sulfonamides towards carbonic anhydrase(CA-II) isoenzyme.In this paper we discuss the QSAR model of same drugs using molecular redundancy as a molecular descriptor towards carbonic anhydrase – IV(CA-IV)isozyme. The regression analysis has shown that out of the
pool of topological indices used, the Molecular Redundancy Index (MRI) is the best one for modeling CA inhibitory properties against the CA-IV isozyme. The results are critically discussed on the basis of statistical parameters

Pages:
13-22
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
DOI:
juc

Copy the following to cite this article:

M.L. GANGWAL1, and SHWETA(Thakur)RATHORE*2, "Role of Molecular Redundancy in modeling carbonic anhydrase (CA-IV) inhibition", Journal of Ultra Chemistry, Volume 9, Issue 1, Page Number 13-22, 2016

Copy the following to cite this URL:

M.L. GANGWAL1, and SHWETA(Thakur)RATHORE*2, "Role of Molecular Redundancy in modeling carbonic anhydrase (CA-IV) inhibition", Journal of Ultra Chemistry, Volume 9, Issue 1, Page Number 13-22, 2016

Available from: http://www.journalofchemistry.org/paper/321/

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