Journal of Chemistry

Papers

Voulume: 14
Issue: 2
Article No. 1
A Facile Synthesis of 6-Amino-4-Aryl-3-Methyl-2,4- Dihydropyrano [2,3-C] Pyrazole-5-Carbonitriles in Aqueous Medium
ROHIT. R. WAKODKAR
Department of chemistry, Saraswati Bhuwan College of Science, Aurangabad, 431004 (M.S.) (India)
GAJANAN SANAP
Department of chemistry, Saraswati Bhuwan College of Science, Aurangabad, 431004 (M.S.) (India)
MAZAHAR FAROOQUI
Department of Chemistry, Dr. Rafiq Zakaria College for Women, Aurangabad (India)
DEEPAK D. KAYANDE
Department of chemistry, Saraswati Bhuwan College of Science, Aurangabad, 431004 (M.S.) (India)
Abstract :

A convenient four-component synthesis of 6-amino-4-alkyl/aryl-3-methyl-2,4-dihydropyrano[2,3- c]pyrazole-5-carbonitriles.They are widely used for industrial purposes and also exhibit a broad range of antimicrobial activity. They are synthesized by using ethylacetoacetate, hydrazine hydrate, malononitrile, and various aldehydes using Tetra n-butyl ammonium bromide (TBAB) as a catalyst and water as solvent under mild reaction conditions. This method has several advantages such as high yield, mild reaction condition, operational simplicity, easy work-up procedure with environment friendly nature.

Keyword : Pyranopyrazoles, Tetra n-butyl ammonium bromide (TBAB) Aqueous medium, Multicomponent reactions
Paper Download Count : 660
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Article No. 2
Synthesis and Charaterisation of Metal chelates of (5-(2,3-dimethyl-1- phenyl-3-pyrazolin-5-one-4-ylazo)-1H-pyrimidine-2,4-dione)
VIDYA V G
University College, M G Road, Palayam, Thiruvananthapuram- 695 034, Kerala, (India)
V SADASIVAN
University College, M G Road, Palayam, Thiruvananthapuram- 695 034, Kerala, (India)
Abstract :

An azo dye UAAP and Mn(II), Co(II), Ni(II), Cu(II) and Zn(II)complexes were synthesized and characterized using elemental analysis, mass spectra, UV- Vis, fluorescence spectra, ESR spectrum, IR spectra, NMR spectra, NLO property, molar conductance and magnetic measurements. The spectral and analytical data reveal that UAAP act as both bidentate and tridentate ligand. The molar conductance data reveal that complexes Co(II), Cu(II) and Zn(II) are nonelectrolytic and Mn(II), Ni(II) 1:2 electrolyte in nature. Based on all data structures were proposed for UAAP and complexes. The UAAP and metal complexes were screened for antimicrobial activity, antioxidant study, DNA cleavage analysis and anticancerous investigation.

Keyword : Azo dye, Uracil,, NLO
Paper Download Count : 545
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Article No. 3
Pre-Monsoon Statistical Analysis of Physicochemical Parameters and Trace Metal in Ground Water of Takhatpur, Bilaspur District, Chhattisgarh, India
RAKESH KUMAR YADAV
Research Scholar Dr. C.V. Raman University, Kargi Road, Kota Bilaspur (C.G.) (India)
M.R. AUGUR
Govt. Agrassen PG College, Bilha Bilaspur (C.G.) (India)
Abstract :

Natural water contaminants due to weathering of rocks and leaching of soil etc. it necessary that the quality of drinking of water should be checked of regular time interval, because due to use of contaminated drinking water. Human population suffers from varied of water borne disease. The availability of good quality water is an indispensable feature for preventing disease and improving quality of life. it is to know details about different physic-chemical and trace metals such as Temperature, pH, EC, Turbidity, TS, TSS, TDS, TH, Alkalinity, DO, BOD, COD, Chloride, Sulphate, Phosphate, Fluoride, Nitrate, Na, K, Ca, Mg, Fe, Zn, Mn, Pb used for testing of water quality. The experimental statistical value of mean, SD & %CV of Dissolved Oxygen (DO), was found in TG2 (5.57mg/L), TG2 (0.38mg/L) & TG4 (6.98mg/L) of pre-monsoon season which is above the maximum limit. And in all the sampling station the observed value of Phosphate (PO4 3 ), Zinc(Zn), Manganese (Mn), Lead (Pb) are below detection limit (BDL) of pre-monsoon season.

Keyword : Pre-Monsoon Ground Water, Statistical Analysis
Paper Download Count : 513
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Article No. 4
Synthesis, characterization and antimicrobial activity of benzo thiazoles and 1,3 oxazine based derivatives of s-triazine
PATEL T. V
Department of Chemistry, Navyug Science College, Surat, Gujarat (India)
MALIK G. M.
Department of Chemistry, Navyug Science College, Surat, Gujarat (India)
Abstract :

In the present study, some new substituted 1,3,5 triazine derivatives with 4-(benzo[d]thiazol-2-yl)aniline and 6-(4-methoxyphenyl)-4-phenyl-2H-1,3-oxazin-2-amine and primary amine were synthesized and evaluated for their in vitro antimicrobial activity against Gram positive and Gram negative strains using a micro dilution procedure. Synthesized compounds P1DH to P15DH prove to be effective with MIC (μg/mL), among them P3DH, P4DH, P5DH, P15DH and P9DH showed excellent activity against a panel of microorganisms. The newly synthesized compounds were characterized using IR, 1H- NMR, 13CNMR, MASS Analysis.

Keyword : Cyanuric Chloride, Different primary amine, antimicrobial activity
Paper Download Count : 517
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