Journal of Chemistry

Papers

Voulume: 13
Issue: 2
Article No. 1
Application of Novel Clay catalyst for the Synthesis of bis-indole derivatives from 2-phenyl-1-H- indole
ISMAIL SHAIKH* 1, 2, MUKTAR SHAIKH2, MAZAHAR FAROOQUI3 and SYED ABED4

1Post Graduate and Research Centre, Maulana Azad College, Aurangabad (M.S.)
2P. G. Department of Chemistry, Shri Anand College Pathardi, Dist. Ahmednagar (M.S.)
3Dr. Rafiq Zakaria College for Womens, Navkhanada Aurangabad, Dist. Aurangabad, (M.S.)
4Government College of Arts and Science Aurangabad, Dist. Aurangabad, (M.S) India

Email address of Corresponding Author: abed3dec@gmail.com, mazahar_64@rediffmail.com

Abstract :

In this study, we report that the novel clay material was found to catalyze electrophilic substitution reaction of 2-phenyl-1-H-indoles with a variety of aromatic aldehydes to excellent yields of bis (indolyl) methanes at room temperature. The efficient synthesis of 2-phenyl-1-H-indoles was achieved by Fischer indole synthesis with addition of phenyl hydrazine and acetophenone.

Keyword : Novel Clay, XRD, EDS, FESEM, 2-phenyl-1-H-indoles, substituted aromatic aldehydes, nanomaterial
Paper Download Count : 970
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Article No. 2
Thiazolo[3,2-a] pyrimidin-5-ones: Design, Synthesis and Antimicrobial Evaluation
BABASAHEB ZINE1, SUNIL JADHAV2, PRASHANT DIXIT4 and MAZAHAR FAROOQUI*2,3

1Department of Chemistry, Bhagwan Mahavidyalaya, Ashti. Dist. Beed-414203(MS), India
2Post Graduate and Research Center, Maulana Azad College, Aurangabad- 431001(MS), India
3 Dr. Rafiq Zakaria College for Women, Aurangabad- 431001(MS), India
4Dr.BabasahebAmbedkarMarathawadaUniversity, Subcampus, Osmanabad (MS), India

Email address of Corresponding Author:mazahar_64@rediffmail.com

Abstract :

Bacterial and fungal infections represent one of the most common health problem that cause functional disability and other complications. Upcoming needs for the clinical drugs candidates for the improvement signifies an exciting and challenging approach to improve the clinical effectiveness of current drugs in the development of new therapeutic approaches. In the existing report, we here report our results for extensive SAR study of novel thiazolo pyrimidin-5-ones derivatives, synthesis, antibacterial and antifungal activity. We are happy to display our most active compounds 5a, 5d, 5e, 5i owned incredible antimicrobial and antifungal potency. Altogether, compound 5i was found to be a lead candidate, displayed maximum potency in both antifungal and antibacterial segments. These findings recommend the prospective to explore this series as antimicrobial and anti-fungal agents

Keyword : Antibacterial, Antifungal, Thiazolo pyrimidin-5-ones, SAR
Paper Download Count : 719
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Article No. 3
Kinetics Studies of Oxidation of Furosemide by Acidic Potassium Permanganate
SAYYED HUSSAIN1, KATAPALLE RAMDAS2, SALIM SAYYED1 and WANKHEDE D.S.3

1P.G. Dept. of Chemistry, Sir Sayyed College of Arts, Commerce and Science, Aurangabad (M.S.) 431001, India
2Late Shankarrao Gutte Gramin Mahavidyalaya, Dharmapuri, Dist. Beed (M.S.), India
3School of Chemical Sciences, S.R.T.M.U.,Nanded (M.S.), India

Email address of Corresponding Author: drhussainsyyd@yahoo.com

Abstract :

The Kinetic of oxidation of Furosemideby potassium permanganate has been studied in the presence of acidic medium. The reaction is first order with respect to KMnO4 as well as Furosemideconcentration. The reaction rate has beendetermined at different temperature and different thermodynamic parameters have been calculated which shows that the reaction rate increase with increase in temperature. With increase in the concentration of acid the reaction rate increases. A suitable mechanism has been proposed.

Keyword : Kinetics, Mechanism, Oxidation, Furosemide, potassium permanganate, thermodynamic parameters
Paper Download Count : 601
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Article No. 4
Calcium Ion Selective Electrode Based on Vinyl Acetic Acid Grafted PVC Ionophore & Determination of Thermodynamic Functions & Its Analytical Application
A. VIJAYALAKSHMI1 and J. THAMARAI SELVI2

1,2 Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women Coimbatore- 641043, Tamilnadu, (INDIA)

Email address of Corresponding Author:- thamaraimuthu1973@gmail.com

Abstract :

A new, efficient Calcium ion selective electrode has been prepared using Vinyl acetic acid grafted PVC based ionophore. The influence of temperature on electrode potential was studied & it can be used in the determination of thermodynamic function like G, H & S. The electrochemical impedance spectroscopy (EIS) technique is also employed to study the electrochemical & surface reactions. It was also successfully used in the analysis of concentration of Calcium ion in various real samples.

Keyword : Calcium (II), Vinyl acetic acid, PVC, Potentiometry, Electrochemical impedance spectroscopy
Paper Download Count : 895
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Article No. 5
Multimetal - multiligand complexes of Hg (II), Cd (II) and Pb (II) ions involving 2-aminosuccinic acid and 5 methyluracil
K. KUMAR and D.K. DWIVEDI

Department of Chemistry, Pt. SNS Govt. P.G. College Shahdol (APS University Rewa M.P.) INDIA

Email address of Corresponding Author:- kumark.chem@gmail.com

Abstract :

Potentiometric study of multimetal-multiligand complexes of toxic metals Hg(II), Pb(II) and Cd(II) with two different ligands amino acid acts as a neurotransmitter or neuromodulator 2- aminosuccinic acid (2-ASA) and pyramidine base 5 methyluracil (5-MU) at silver-silver chloride electrode forming the binary, ternary and quaternary complexes having great significance for living beings. The protonation constants, stability constants, titration curves and speciation curves were studied by using special computer programme SCOGS and ORIGIN which gives correct and accurate percentage information of the complex formation.

Keyword : Potentiometric Studies, 2- ASA, (5-MU), SCOGS.ORIGIN
Paper Download Count : 746
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Article No. 6
Quantum chemistry calculations of 2-aminopyrimidine-5-carbonitrile Dye Sensitizer for Solar Cells
S. ARUL1 and T. SENTHILNATHAN2

1Assistant Professor, Department of Physics, GRT Institute of Engineering and Technology, Tiruttani-631209
2Professor, Department of Physics, Velammal Engineering College, Chennai – 600 066

Email address of Corresponding Author:- arulvenkt@gmail.com

Abstract :

Quantum chemistry calculations of energies, geometries, electronic structures, polarizabilities, and hyperpolarizabilities of organic dye sensitizer 2-aminopyrimidine-5-carbonitrile were studied based on ab initio HF and Density Functional Theory (DFT) using the hybrid functionals B3LYP. Ultraviolet-visible (UV-Vis) spectrum was investigated by Time Dependent DFT (TDDFT). Features of the electronic absorption spectrum in the visible and near- UV regions were assigned based on TDDFT calculations. The electronic absorption bands are assigned to ππ* transitions. Calculated results suggest that the three excited states with the lowest excited energies in 2-aminopyrimidine-5-carbonitrile is due to photo induced electron transfer processes. The interfacial electron transfer between semiconductor TiO2 electrode and dye sensitizer 2-aminopyrimidine-5-carbonitrile is due to an electron injection process from excited dye to the semiconductor’s conduction band. The role of amine and nitrile group in 2-aminopyrimidine-5-carbonitrile geometries, electronic structures, and electronic absorption spectra were analyzed in Dye sensitizer solar cell (DSSC) give good conversion efficiency.

Keyword : Dye sensitizer, Density functional theory, Electronic structure, Absorption spectrum
Paper Download Count : 809
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