aDepartment of Microbiology, Gujarat Vidyapith Sadra Dist-Gandhinagar Gujarat India
bBiogas Research and Extension Centre, Gujarat Vidyapith Sadra Dist-Gandhinagar Gujarat India
cAssistant Professor Biogas Research and Extension Centre Gujarat Vidyapith Sadra Dist-Gandhinagar Gujarat India
Email:- mayurchemistry@yahoo.co.in
A laboratory experiment was conducted to find out the suitability of water extract of Catharanthus roseus flowers as indicator in different acid-base titrations viz strong acid v/s strong base (0.01, 0.1 and 1M HCl with same concentration of NaOH); weak acid v/s strong base (0.1M CH3COOH with 0.1M NaOH); and weak base v/s strong acid (0.1M NH4OH with 0.1M HCl). The water extract was obtained by simple boiling of 10%w/v solution of Catharanthus roseus flowers in distilled water. The color change of water extract of flower at different pH values was find out pH metrically and for standardization it was compared with phenolphthalein (1% w/v in ethanol) and methyl orange (1% w/v in ethanol) for the same system. The theoretical values of pH at various stages were compared with pH change of natural indicator in this range. Results reveal that the water extract of Catharanthus roseus flowers shows the color change at the equivalence point for HClNaOH and NH4OHHCl titration but it failed to produce color change at equivalence point for CH3COOHNaOH titration.
1MES College of Pharmacy, Bangalore india
2KVR Siddartha College of Pharmacy, Vijayawada India
Government College of Parmacy, Bangalore India
Email:- bksoni19@gmail.com
A series of novel pyrazoles were synthesized starting from 4- fluoro-3-chloroaniline by condensation with aromatic aldehydes to give chalcones which were cyclized with hydrazine to obtain pyrazoles. The chlorine replaced various aromatic amines to obtain the final derivatives. The final compounds evaluated for in vitro bovine serum denaturation assay and in vivo antinflammatory activity by carrageenan induced rat paw oedema. The study indicated the importance of chlorine at the para position of the aromatic ring in enhancing antiinflammatory activity. Correlation with enzyme inhibition scores also explained.
Post Graduate Department of Chemistry College of Commerce, Patna India
Email:-anilcoc2013@gmail.com
In this article, the spectral characteristics of horseradish peroxidase in aqueous buffer as well as nonionic reverse micelles is reported at various pH values. It is found that the soret band of HRP slightly shifted in acidic as well as in alkaline media with respect to the neutral pH( pH 7.00). The shifting of λmax could be related with the conformational change of the enzyme molecule at different pH values. Further, the absorption spectra of the peroxidase in aqueous buffer as well as in nonionic micellar media at Wo = 15, pH = 7.00, is found virtually unchanged. The molar extinction coefficient (ε) of peroxidase at λ = 403 nm remains more or less constant till pH 11.8 inside the aqueous pool of the reverse micellar system and above this it falls rapidly. The fall of εvalue indicates that there is a change of conformation of the enzyme molecule after pH 11.8
1MES College of Pharmacy, Bangalore india
2KVR Siddartha College of Pharmacy, Vijayawada India
3Government College of Parmacy, Bangalore India
Email:- bksoni19@gmail.com
A series of novel pyrazoles were synthesized starting from 4- fluoro-3-chloroaniline by condensation with aromatic aldehydes to give chalcones which were cyclized with hydrazine to obtain pyrazoles. The chlorine was replaced with various aromatic amines to obtain the final derivatives. Evaluation of antibacterial activity against Staphylococcus aureus and Escherechia coli highlights the importance of methyl substitution and requirement of high lipophilicity. Ferric ion reduction studies indicate the requirement of requirement of electron releasing aromatic substitutions for enhanced antioxidant activity
Professor Department of Chemistry
Gov. PG College , Damoh MP India
The Present paper deals the presence of potential antitumor activity of the compounds isolated from xanthium species of composite a family. Enough evidences prove that sesquiterpenoidal lactones present the above plants posses good anti cancerous reputation.
Department of Applied Chemistry Priyadarshini JL college of Engineering new Nandanvan nagpur MS India
Waste of electronics/ electrical goods that have reached their end of life. Electronic products often contain hazardous and toxic materials and should not be dumped with other wastes. Along with China, India is largest importer of E-waste from developed countries like US; UK and Japan. In India 90% of mobile equipment are imported. The rate of e-waste generation is increasing by 10% every year1
Prof. & Head Department of Chemistry MLSM College Dharbhanga India
Trisubstituted Pyrazolines were prepared. Metal ligand stability constant of complex compounds of Co(II), Ni(II), Cu(II), Zn (II) & Cd (II) were determined by Calvin – Bjerrum pH metric titration technique modified by Irving & Rossotti at two temperatures ie. 303 K & 308 K in water : dioxane mixture in 1:1 ratio by volume. Ionic strength of the solution was kept constant ( 0.1M) using NaNO3 solution. The values of stepwise stability constant log K1 & log K2 were calculated by half integral method and was further verified by mid point calculation method and linear plot method. The observed stability constant value are in the order Cd(II) < Zn (II) < Co(II) < Ni (II) < Cu (II). This result is in conformity with the Irving – Williams natural order of stability. The values of G 0 and H 0 for all the metal chelates were found to be negative indicating that the chelate formation is a spontaneous process.